Light of the ALBA Synchrotron to study Alzheimer’s
Researchers of the ALBA Synchrotron and the Autonomous University of Barcelona (UAB) have analyzed with synchrotron light how they are, where they are located and what effects different Alzheimer’s aggregates have on in vitro neurons.
These results, which have been published in the journal Analytical Chemistry, open the way to better understand how this disease develops.
Researchers of the Alba Synchrotron and the Autonomous University of Barcelona (UAB) analyze with light of the Alba Synchrotron how they are, where they are located and what effect the different aggregates of Alzheimer’s have on in vitro neurons.
This is reported by the Synchrotron in a statement in which it explains that the results of this study have been recently published in the journal Analytical Chemistry.
The researchers carried out the experiment with infrared in the synchrotron of Cerdanyola del Vallès but also in that of Grenoble (France) and the effect of two types of amyloid peptide aggregates (fibrillar and amorphous) was analyzed.
The results indicate that the amorphous aggregates provoke a degree of oxidation superior to the others, while, being of special importance, the in situ location of these aggregates in the cultivated cells has been obtained.
The results agree with previous research and support the hypothesis that amyloid peptides are the cause of cellular oxidation that is associated with Alzheimer’s.
The study, as explained by the center, has served to advance the characterization of these amorphous aggregates and consider them as a potential toxic agent in the start-up and development of the disease.
Video, text and image source: ALBA Synchrotron
Text source: https://www.cells.es/es/actualidad/noticias/analizan-con-luz-de-sincrotron-los-mecánismos-del-alzheimer
Source video: ALBA Synchrotron
Related Article: Sanbot & Mazda / Sanbot Elf